Monthly Archives: April 2017


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Pain is the main reason people nowadays seek medical help. It can interfere with work, sleep, activities of daily living and the general quality of life. Pain relievers are one of the most common prescriptions and sought after drugs in the market. Hydrocodone and Acetaminophen are examples of these medications. Hydrocodone belongs to a group of drugs called narcotic pain relievers while Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone. A combination of both is used to relieve moderate to severe pain.

Pill imprint Watson 853 is also known as Acetaminophen and hydrocodone bitartrate 325 mg / 10 mg and belongs to the drug class narcotic pain relievers. It is used to treat back pain, cough, rheumatoid arthritis, pain, and many more.


Oral capsule, oral elixir, oral liquid, oral solution, oral syrup, oral tablet


a) General

• Do not use this medication if you are allergic to acetaminophen (Tylenol) or hydrocodone.
• Should be taken with increased fiber diet and 6 to 8 full glasses of water daily to help prevent constipation.
• Be careful when driving or doing activities that require you to be awake and alert. Acetaminophen and hydrocodone can cause side effects that may impair your thinking or reactions.
• Avoid drinking alcohol while taking this medicine as it increases the risk for liver damage.
• Inform the doctor if you plan to get pregnant, or if you are pregnant or breastfeeding. It may be harmful to the unborn and nursing baby.
• Caution with use to elderly. They are sensitive to effects of this medicine.
• Do not immediately stop taking the medication or take in larger amounts, or use it for longer than recommended by your doctor.
• Take exactly as prescribed and follow directions on the prescription label. Measure the liquid form with a dose-measuring device, overdose can harm the liver.

b) Clinical

• Inform your treating physician that you are taking acetaminophen and hydrocodone as it may alter urine tests.
• Inform the doctor of any past and present illnesses or diseases as well as any medications taken.
• Inform the doctor that you are taking the medicine before undergoing surgery.

c) Storage

• Store acetaminophen and hydrocodone at room temperature away from moisture and heat.
• Keep in a secure place. Hydrocodone is a habit-forming drug and must not be used by anyone to whom it is not prescribed.

Side Effects

a) Minor Side Effects

• feeling anxious, dizzy, or drowsy;
• mild nausea, vomiting, upset stomach, constipation;
• headache, mood changes;
• blurred vision;
• ringing in your ears; or
• dry mouth

**Stop taking the medicine and call the doctor with these symptoms:

b) Allergic Reactions

• hives; difficulty breathing; swelling of your face, lips, tongue, or throat

c) Major Side Effects

• shallow breathing, slow heartbeat;
• feeling light-headed, fainting;
• confusion, fear, unusual thoughts or behavior;
• seizure (convulsions);
• problems with urination; or
• nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Signs of Overdose

• extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.

Seek emergency help in case of an overdose as this can be fatal and talk to your doctor about any side effect that seems unusual or bothersome.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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TEVA 149


Pain is a physical suffering or discomfort caused by an illness or injury. It is the main reason people seek medical help and the most common complaint of people worldwide. The commonly used medication for pain nowadays is Teva 149 also known as Naproxen 500mg. It is an effective pain reliever available over the counter and at a low cost.

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) and works by reducing hormones that cause inflammation and pain in the body. It provides relief of minor aches and pains in muscles, bones, and joints; mild-to-moderate pain accompanied by inflammation in injuries (e.g., sprains and strains); and menstrual cramps. It is used to treat headache, back pain, sciatica, gout, symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile rheumatoid arthritis.

When naproxen should not be used

• allergic to naproxen
• with severe allergic reaction to aspirin or another NSAIDs (eg, ibuprofen, celecoxib)
• recently had or will be having bypass heart surgery
• severe liver and kidney problems
• pregnant, planning to become pregnant, or are breast-feeding
• taking another medicine that contains naproxen
• with inflammatory bowel disease such as ulcerative colitis, Crohn’s disease
• with bleeding disorder
• have an ulcer or bleeding in the stomach or intestines
• have bleeding in the brain
• recent rectal or anal inflammatory lesions and bleeding
• taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement to prevent any drug interactions.
• drinking alcohol
• taking aspirin with naproxen
Suppository form of naproxen should not be given to children below 12 years of age.

Side Effects

A side effect is an unwanted response to a medication when it is taken in normal doses. It can be mild or severe, temporary or permanent.

Signs of an allergic reaction to naproxen
• sneezing, runny or stuffy nose;
• wheezing or trouble breathing;
• hives
• swelling of your face, lips, tongue, or throat

Signs of a heart attack or stroke
• chest pain spreading to your jaw or shoulder,
• sudden numbness or weakness on one side of the body
• slurred speech
• feeling short of breath

Common Side Effects
• indigestion, heartburn, stomach pain, nausea;
• headache, dizziness, drowsiness;
• bruising, itching, rash;
• swelling; or
• ringing in your ears

Major Side Effects
• shortness of breath (even with mild exertion);
• swelling or rapid weight gain;
• the first sign of any skin rash, no matter how mild;
• signs of stomach bleeding – bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
liver problems – nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• kidney problems – little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;
low red blood cells (anemia) – pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or
severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Signs of overdose
• Bleeding under the skin
• confusion about identity, place, and time
• muscle tremors
• restlessness
• sleepiness

This is not a complete list of drug reaction and side effects. Some minor side effects disappear once the body gets used to the medication, while some may lead to serious problems. Discuss with your doctor how to manage symptoms or if it worries you. Immediately stop taking the medication and seek emergency help if you experience allergic reactions, major side effects or overdose.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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Pliva 433

Pliva 433, sometimes known as trazadone, is one of the most commonly prescribed drugs for dealing with severe depression. Here, we are going to look at some of the most common uses of Pliva 433, as well as highlight some of the side-effects that a person taking this medication may deal with.


Pliva 433 is only really prescribed when it comes to treating severe depression. There is evidence that it can significantly improve your mood. In addition to this, it can increase your appetite and boost your overall energy levels.

If you are suffering from insomnia related to your depression, then the Pliva 433 will make it a bit easier for you to function.

The drug works by helping to restore the balance of serotonin that you have in your brain. Basically, it helps to level out things a little bit. This is what will help to eradicate your depression while you are taking the medication.

How to Take Pliva 433

You will need to take as directed by your doctor. In most cases, you will be taking it once or twice per day with your food. It is important that you only take it as instructed as the risk of overdose with Pliva 433 is very real. You want to avoid this!

You may not be prescribed Pliva 433

If you are allergic to nefazodone then you will not be prescribed Pliva 433 by your doctor. You will also likely not be prescribed it if you or your immediate family has a history of the following:

  • Bipolar disorder
  • History of suicide attempts or suicide.
  • Heart disease. This includes irregular heartbeats or if you have had a heart attack in the past.
  • Liver disease
  • Kidney disease
  • Problems with your blood pressure.
  • Glaucoma

If you are taking any MAO inhibitors, your doctor will not prescribe you with this drug at all. This is because there could be a fatal interaction between the two drugs. You should not take any MAO inhibitors for 2 weeks after the conclusion of the Pliva 433 treatment otherwise you will cause yourself issues (i.e. it could lead to death)


There are several side-effects to using Pliva 433. However, thankfully, they do not seem to appear all that much. The most common side-effects are:

  • Change in weight
  • Diarrhea
  • Drowsiness
  • Dizziness
  • Muscles aches and pains
  • Dry mouth
  • Constipation
  • Change in your interest in sex may change.

They are just minor side-effects and it is unlikely that you will need to talk to your doctor about them. However, there are some serious side-effects which you will need to tell your doctor about. This includes:

  • Shaking
  • Regular nightmares
  • If you hear a ringing in your ears.
  • You are unable to urinate
  • There is blood in your urine
  • You suffer from a shortness of breath.

If you suffer from any of the following, you need to seek medical attention right away:

  • Pain in your chest, jaw, left arm.
  • Fainting
  • Irregular heartbeat
  • Fast heartbeat
  • Seizures
  • Changes in vision
  • Widened pupils
  • Problems with your eyes.


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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Alprazolam is a benzodiazepine which works by slowing down chemicals in the brain that may be unbalance in people with anxiety.

It is used to treat tinnitus, borderline personality disorder, anxiety disorders, panic disorders, anxiety caused by depression, and many more. It may also be used for purposes other than those mentioned.

Considerations before taking Alprazolam:

Take caution when buying alprazolam on the Internet or from vendors outside the United States as they may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Alprazolam should not be taken if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to alprazolam or similar medicines (Valium, Ativan, Tranxene, and others)

Inform the doctor of any medications taken as these may have side effects or conditions such as:

• seizures or epilepsy;
• kidney or liver disease (especially alcoholic liver disease);
• asthma or other breathing disorder;
• open-angle glaucoma;
• a history of depression or suicidal thoughts or behavior;
• a history of drug or alcohol addiction; or
• if you also use a narcotic (opioid) medication.

The doctor should be informed if you plan to get pregnant. Do not use Alprazolam if pregnant or breastfeeding. It can cause birth defects and can cause life-threatening withdrawal symptoms to the baby after it is born. It can also harm the nursing baby since the medication can pass through breast milk.

Alprazolam is not approved for use by anyone younger than 18 years old.

Considerations when using Alprazolam:

Allow orally disintegrating tablet to dissolve in your mouth without chewing and do not swallow it whole.

Extended-release tablet should be swallowed whole. Do not crush, chew, or break the tablet.

Measure liquid medicine with a dose-measuring device, ask your pharmacist for one.

Avoid drinking when taking the medication as it increases its side effects.

Avoid driving or any activity requiring alertness. Alprazolam may impair your thinking or reactions.

Use caution to avoid falling or accidental injury while taking alprazolam especially in elderly patients.

Alprazolam is habit-forming. Misuse can cause addiction, overdose, or death.

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Take alprazolam as prescribed by the doctor. Never stop abruptly or use in larger amounts, or for longer than prescribed.

Frequent medical tests may be required with long-term use.

Store at room temperature away from moisture and heat and in a place where others cannot get to it.

Side Effects:

Allergic Reaction:

• hives; difficulty breathing; swelling of face, lips, tongue, or throat

Common Side effects:

• drowsiness, feeling tired;
• slurred speech, lack of balance or coordination;
• memory problems;
• feeling anxious early in the morning.

Major Side effects:

• depressed mood, thoughts of suicide or hurting yourself;
• racing thoughts, increased energy, unusual risk-taking behavior;
• confusion, agitation, hostility, hallucinations;
• uncontrolled muscle movements, tremor, seizure (convulsions);
• pounding heartbeats or fluttering in your chest.

Get emergency medical help in case of allergic reaction and call the doctor in case of major side effects. This is not a complete list of precautions and side effects. Discuss with your doctor any reaction or any questions you want to clarify for safe use or anything that bothers you with its use.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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IP 466

Pills with the identification marking of IP 466 are also known as Ibuprofen 800 mg. It is a nonsteroidal anti-inflammatory drug (NSAID) used to treat, fever, inflammation, and other minor to moderate pains such as arthritis, toothache, back pain, sciatica, muscle pain, headache, and many more. Most over-the-counter ibuprofen pills come in 200 mg doses; higher doses are often prescribed by doctors and are used in adults and children who are at least 6 months old.

Ibuprofen comes in oral capsule, oral capsule liquid filled, oral suspension, oral tablet, oral tablet chewable and some as an intravenous solution.


 Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

With long term use or high doses, Ibuprofen can increase the risk of fatal heart attack or stroke even to people without the risk factors for heart disease.

Its use can also cause stomach or intestinal bleeding which can occur without warning and which can be fatal.

Ibuprofen should not be taken if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Inform your doctor of any illness and the medicines being taken as these may have an effect to Ibuprofen or any of its components.

Do not use this medicine without a doctor’s advice if you are pregnant or breastfeeding.

Do not give to children younger than 2 years old without doctor’s advice.

Avoid taking with aspirin or unless prescribed by the doctor.

Avoid drinking alcohol as this may increase stomach bleeding.

While this medication works really well to relieve many different types of pain, there can be some unintended and unwanted ibuprofen drug side effects.

Side Effects

In summary, commonly reported side effects of ibuprofen include: upset stomach, mild heartburn, nausea, vomiting, bloating, gas, diarrhea, constipation, dizziness, headache, nervousness, mild itching or rash and ringing in your ears. Some of the major side effects include: changes in your vision, shortness of breath (even with mild exertion), swelling or rapid weight gain, skin rash, stomach bleeding either coughing up or passing out bloody or tarry stools, signs of liver and kidney problem such as jaundice (yellowing of skin or eyes), clay colored stools, dark urine to little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath, signs of anemia such as pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating, and severe skin reaction such as fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Signs of an allergic reaction to ibuprofen are sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.

Signs of a heart attack or stroke are chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, and feeling short of breath.

This is not a complete list of side effects. Some side effects may occur and may not need medical attention since the body is adjusting to the medicine during treatment, while some of them may go away.  Seek emergency medical help in case of major side effects, allergic reaction or if signs of heart attack occur.  Call the doctor if any of the following side effects continue, are bothersome or if you have any questions about them.


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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IP 190

Pain is a physical suffering or discomfort caused by an illness or injury.  It may be acute which can be intense and may be an indication of an injury, or chronic, which lasts much longer and can be mild or intense (severe). The most common medication for pain is IP 190, also known as Naproxen 500 mg. They are available over the counter and at a low cost.

 Naproxen Overview

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) which works by reducing hormones that cause inflammation and pain in the body. It is used to treat conditions such as headache, back pain, sciatica, arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

It may be in the form of oral suspension, oral tablet, oral delayed release tablet, oral tablet, extended release, oral capsule, compounding powder, oral and topical kit.


Naproxen should not be used by those with asthma and with history of allergic reaction to aspirin or other NSAID (nonsteroidal anti-inflammatory drug).

It increases the risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine. Use therefore as prescribed.

This medicine should not be used just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Naproxen may also cause stomach or intestinal bleeding which can be fatal and occurs without warning.

Seek immediate help with chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

Ask a doctor before using this medicine if you are pregnant. It may harm the unborn baby if taken during the last 3 months of pregnancy. It may also interfere with ovulation, causing temporary infertility.

Naproxen should not be used when breastfeeding. It can pass into breast milk and may cause side effects to the nursing baby.

It is not approved for use by anyone younger than 2 years old and should not be given to a child without medical advice.

What to avoid while taking Naproxen?

Avoid drinking alcohol as it may increase the risk of stomach bleeding.

Avoid taking aspirin.

Ask your doctor before taking any other medication for pain, arthritis, fever, or swelling. Many medicines available over the counter contain aspirin, salicylates, or other medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking certain products together can cause you to get too much of this type of medication.

Ask your doctor before using antacids; some make it harder for your body to absorb naproxen.

Side Effects

 Common naproxen side effects are indigestion, heartburn, stomach pain, nausea, headache, dizziness, drowsiness, bruising, itching, rash, swelling or ringing in your ears.

Major Side Effects

  • Belching
  • bruising
  • difficult or labored breathing
  • feeling of indigestion
  • headache
  • itching skin
  • large, flat, blue, or purplish patches in the skin
  • pain in the chest below the breastbone
  • skin eruptions
  • stomach pain
  • swelling
  • tightness in the chest

Signs of an allergic reaction are sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.

Signs of a heart attack or stroke include: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, and feeling short of breath.

Symptoms of Overdose

  • Bleeding under the skin
  • confusion about identity, place, and time
  • muscle tremors
  • restlessness
  • sleepiness

Your health care professional may be able to help you prevent or reduce naproxen side effects, but do check with them if any of the following side effects continue or if you are concerned about them. It is always best to consult your doctor before taking the medication and take only as prescribed. Immediately call a doctor if severe/major side effects occur.


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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Pliva 434

Depression is a condition more than just a passing blue mood, a “bad day,” or temporary sadness. It is characterized by a low mood that can sometimes appear as irritability. Oftentimes, a person with depression is not able to enjoy activities that he or she normally enjoys. Major depression on the other hand is a profound sadness or a sense of despair lasting at least two weeks, but usually they go on much longer. Both can be treated naturally but some require medication especially with major depressive disorder. The most common prescription is PLIVA 434 also known as Trazodone hydrochloride 100 mg. Trazodone is used in the treatment of insomnia; anxiety; sedation; fibromyalgia; major depressive disorder (and more), and belongs to the drug class phenylpiperazine antidepressants. It is a common antidepressant medicine sometimes called “mood elevator” which affects chemicals in the brain that may be unbalanced in people with depression.

About Trazodone

Trazodone is the generic name for the brand-name product called Oleptro. It is available as a tablet or an extended-release tablet. The doctor prescribes the medication and gives an advice on how much to take and when to take it. It should be taken the same time each day and not on excessive or fewer doses. Always follow doctor’s instructions as taking this medication incorrectly or stopping immediately causes side effects which may worsen your condition.

Common Side Effects

Before taking trazodone, talk with your doctor about any health conditions you have or have had in the past such as:

  • Bipolar disorder
  • Kidney or liver disease
  • Blood or bleeding disorders
  • Heart disease
  • A heart rhythm problem called long QT syndrome
  • Low blood pressure
  • Low blood sodium
  • Recent heart attack

In summary, Commonly reported side effects of trazodone include: blurred vision, dizziness, drowsiness, headache, nausea, vomiting, and xerostomia. Other side effects include: syncope, edema, ataxia, confusion, diarrhea, hypotension, insomnia, sedation, and tachycardia. Serious side effects which may need emergency attention include:

  • Signs of an allergic reaction: itching or hives; swelling or tingling in the face, lips, mouth, throat, or hands; chest pain or tightness; or difficulty breathing or swallowing
  • Confusion, weakness, or decreased coordination
  • Stiff, rigid muscles or uncontrollable muscle twitching or tremors
  • Fever, sore throat, or other signs of infection
  • Fast, pounding, or irregular heartbeat
  • Hallucinations
  • Painful, prolonged erection
  • Extreme dizziness, light-headedness, or fainting
  • Unusual bleeding or bruising

It is important to inform the doctor if you are pregnant, breast-feeding, or planning to become pregnant. It should not be taken if you have ever had a bad reaction to this medicine or are allergic to any of its ingredients. Also, refrain from driving or operating heavy machinery until you know how it affects you. Make sure all the doctors who you see, including your dentist, know that you take trazodone. This is especially important if you need any type of surgery, because it may react with anesthetic medicines used during certain procedures. Tell your doctor about all the medicines you take, including over-the-counter medicines, herbal remedies, vitamins, and supplements. Give your doctor an up-to-date list of all your medicines so that he or she can be sure they will not interact with trazodone.

Warnings and Precautions

Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs. Suicide is a known risk of depression and certain other psychiatric disorders and these disorders themselves are the strongest predictors of suicide. There has been a long standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment.

All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for emergence of agitation, irritability, unusual changes in behavior, clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases and to report such symptoms immediately to healthcare providers.


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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