Category Archives: Reumophan


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If you are looking for a medication that will offer you relief from rheumatic and muscular pain, sprains, dislocations, contractures, pain for over effort and exercise or pain in different parts of the body, the best medicine is known as reumophan.

Reumophan is basically an over-the-counter medication that serves as a muscle relaxant. It is very useful for patients with a medical history of gastrointestinal intolerance to non-steroidal anti-inflammatory drugs. This medicine can also be helpful for those who are experiencing bursitis, acute gout, muscle spasms, lumbago, painful vertebral syndrome, osteoarthritis, arthralgia, and so much more.

Therapeutic Uses and Description about Reumophan

Reumophan is generally the combination of an NSAID called ketoprofen with chlorzoxazone, analgesic that offers muscle relaxant effect as well as calcium carbonate that might prevent and attenuate gastrointestinal intolerance due to NSAIDs and duodenal or gastric ulcers in those who have chronic-degenerative diseases.

Ketoprofen is actually metabolized in liver and sixty to seventy-five percent of the dosage appears in the urine, primarily as glucuronide metabolite as well as less than ten percent excreted as an unchanged drug. Ketoprofen’s elimination half-life is two to four hours. This non-steroidal anti-inflammatory drug comes with analgesic and anti-inflammatory properties. It also inhibits prostaglandin synthesis aside from the factor inhibit leukocyte migration particular macrophages and neutrophils that are constituents of the inflammation’s cellular factor. This is excreted primarily in urine and in some ways completely after a day.

Chlorzoxazone is absorbed rapidly from gastrointestinal tract, which is metabolized to six-hydroxychlorzoxazone. This is excreted in urine in about 1.1 hour. For those who don’t know, it’s a muscle relaxant and doesn’t exert direct effect on one’s body muscles. However, it can act on brain subcortical level and spinal cord to inhibit some reflections that are associated with muscle spasms. Some of the therapeutic effect of this substance is basically associated to the sedative properties. Aside from that, Chlorzoxazone attenuates muscle spasm by acting on the spinal neurons. This induces relaxation of the muscles, reduced muscle tone, and it doesn’t generate neuromuscular blockade. This is absorbed easily and will be excreted in one’s urine within 6 to 24 hours. This is used as muscle relaxant for breaking vicious cycles associated with antirheumatic, analgesic, and anti-inflammatory.