Pliva 433

Pliva 433

Pliva 433, sometimes known as trazadone, is one of the most commonly prescribed drugs for dealing with severe depression. Here, we are going to look at some of the most common uses of Pliva 433, as well as highlight some of the side-effects that a person taking this medication may deal with.


Pliva 433 is only really prescribed when it comes to treating severe depression. There is evidence that it can significantly improve your mood. In addition to this, it can increase your appetite and boost your overall energy levels.

If you are suffering from insomnia related to your depression, then the Pliva 433 will make it a bit easier for you to function.

The drug works by helping to restore the balance of serotonin that you have in your brain. Basically, it helps to level out things a little bit. This is what will help to eradicate your depression while you are taking the medication.

How to Take Pliva 433

You will need to take as directed by your doctor. In most cases, you will be taking it once or twice per day with your food. It is important that you only take it as instructed as the risk of overdose with Pliva 433 is very real. You want to avoid this!

You may not be prescribed Pliva 433

If you are allergic to nefazodone then you will not be prescribed Pliva 433 by your doctor. You will also likely not be prescribed it if you or your immediate family has a history of the following:

  • Bipolar disorder
  • History of suicide attempts or suicide.
  • Heart disease. This includes irregular heartbeats or if you have had a heart attack in the past.
  • Liver disease
  • Kidney disease
  • Problems with your blood pressure.
  • Glaucoma

If you are taking any MAO inhibitors, your doctor will not prescribe you with this drug at all. This is because there could be a fatal interaction between the two drugs. You should not take any MAO inhibitors for 2 weeks after the conclusion of the Pliva 433 treatment otherwise you will cause yourself issues (i.e. it could lead to death)


There are several side-effects to using Pliva 433. However, thankfully, they do not seem to appear all that much. The most common side-effects are:

  • Change in weight
  • Diarrhea
  • Drowsiness
  • Dizziness
  • Muscles aches and pains
  • Dry mouth
  • Constipation
  • Change in your interest in sex may change.

They are just minor side-effects and it is unlikely that you will need to talk to your doctor about them. However, there are some serious side-effects which you will need to tell your doctor about. This includes:

  • Shaking
  • Regular nightmares
  • If you hear a ringing in your ears.
  • You are unable to urinate
  • There is blood in your urine
  • You suffer from a shortness of breath.

If you suffer from any of the following, you need to seek medical attention right away:

  • Pain in your chest, jaw, left arm.
  • Fainting
  • Irregular heartbeat
  • Fast heartbeat
  • Seizures
  • Changes in vision
  • Widened pupils
  • Problems with your eyes.


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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